Tuesday, March 19, 2013

Supreme Court takes up Arizona voter law

By Pete Williams, Justice Correspondent, NBC News

Arizona is asking the Supreme Court to uphold its process for registering voters, one that several states say will reduce voter fraud but that civil rights groups insist is an effort to discourage participation by legal immigrants.

The justices hear arguments Monday in a dispute over Proposition 200, adopted by Arizona voters in 2004.? It requires residents to submit proof of citizenship when they register to vote in the state.

REUTERS/Molly Riley

The Supreme Court building seen in Washington May 20, 2009.

A coalition of civil rights groups says the law "requires naturalized citizens -- predominantly Latinos and Asians -- to surmount additional and unique hurdles to exercise their fundamental right to vote."

The case presents a conflict between two powers granted in the Constitution -- the right of states to set their own rules for electing federal officials and the authority given Congress to change those laws.

A decade ago, Congress passed the National Voter Registration Act, better known as the Motor Voter law. It requires all states to treat an application for a driver's license as a request for voter registration.

Applicants can also register by mail, in addition to the traditional method of showing up in person at a local election office. Under the Motor Voter law, each state is required to "accept and use" a federal registration form or their own version of it, as long as it deemed to be equivalent.?

U.S. citizenship is a requirement to vote in any federal election, and the federal form requires applicants to state, under penalty of perjury, that they are American citizens. But Arizona's Proposition 200 goes further, requiring applicants to provide some form of proof at the time they want to register.

The challengers argue that it's a burden for naturalized citizens to provide the proper documentation. Using a naturalization document for proof, for example, requires an applicant to show up in person, because federal law prohibits making a copy of it. And they say the state's records are incomplete, lacking data that would allow election officials to accept some other forms of proof, such as any Arizona driver's license issued before 1996.

"Often, naturalized citizens must submit a voter registration application multiple times before they successfully register to vote," says a coalition of Latino and Asian American groups.

A federal appeals court ruled that Arizona went too far, departing so far from the Motor Voter act that the state was essentially rejecting the federal form.

Not so, says the state.? "The requirement that applicants provide additional evidence to support their application does not constitute a 'rejection' of the federal form any more than an identification check at at airport gate entrance constitutes a 'rejection' of a passenger's ticket," says Arizona's legal brief in the Supreme Court.

Three other states have nearly identical laws -- Alabama, Georgia and Kansas. They've joined Arizona in urging the court to uphold the additional requirements for proof of citizenship.

If the Supreme Court agrees with Arizona, states would have broader powers to impose their own registration requirements. ?A ruling will come some time before July.

This story was originally published on

Source: http://nbcpolitics.nbcnews.com/_news/2013/03/18/17326321-supreme-court-takes-up-arizona-voter-registration-law?lite

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Sunday, March 17, 2013

Feedly picks up over 500,000 Google Reader defectors

DNP 500,000 Google Reader users defect to Feedly

It looks like Feedly's promises of a "seamless transition" worked. The newsfeed service recently reported that more than 500,000 Google Reader users have joined its ranks following the announcement that the popular aggregator will close this summer. It multiplied its bandwidth ten times over, added new servers to cope with the sudden influx and hopes to keep the service up as much as possible as more users pour in. In an effort to keep its new clientele happy, Feedly has promised to listen to suggestions and add new features on a weekly basis as well. But if it doesn't, don't worry; we suspect there'll be many more alternatives pitching for your RSS feeds over the coming weeks.

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Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/R3-FktzsJxw/

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Guilty verdicts in Steubenville high school rape trial

The judge in the Steubenville, Ohio rape case finds the two defendants are 'adjudicated delinquent' on all three counts which is equivalent to a finding of guilty in adult court.

By Andrew Welsh-Huggins, The Associated Press

STEUBENVILLE, Ohio ? Two Ohio high school football players have been found guilty of raping a drunken 16-year-old girl in a case that roiled a small city and stirred reaction from activists online.

The trial of two Ohio high school football players accused of raping a 16-year-old girl resumed on Saturday. NBC's Ron Allen reports.

Judge Thomas Lipps ruled Sunday in juvenile court that Steubenville High School students Trent Mays and Ma'Lik Richmond are guilty of attacking the girl after an alcohol-fueled party last August.

The 17-year-old Mays and 16-year-old Richmond were charged with digitally penetrating the West Virginia girl, first in a car and then in a house. They could be held in a juvenile jail until they turn 21.

The case divided the community amid allegations that more students should have been charged and led to questions about the influence of the football team, a local source of a pride.

Related:

Prosecution, defense rest their cases in Steubenville rape trial

Steubenville high school rape trial zeroes in on texts, photos, video

As rape trial opens, prosecutors says girl was 'too impaired to say no'

? 2013 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://usnews.nbcnews.com/_news/2013/03/17/17346127-verdict-in-steubenville-high-school-rape-trial?lite

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Saturday, March 16, 2013

CITES makes historic decision to protect sharks and rays

Friday, March 15, 2013

CITES plenary today accepted Committee recommendations to list five species of highly traded sharks under the CITES Appendices, along with those for the listing of both manta rays and one species of sawfish. Japan, backed by Gambia and India, unsuccessfully challenged the Committee decision to list the oceanic whitetip shark, while Grenada and China failed in an attempt to reopen debate on listing three hammerhead species. Colombia, Senegal, Mexico and others took the floor to defend Committee decisions to list sharks.

"We are thrilled with this result and the groundswell of government commitment that made it happen," said Amie Brautigam, Marine Policy Advisor for Wildlife Conservation Society. "These hard-fought decisions to secure CITES regulations on international trade in sharks and rays are based on a solid foundation built over two decades, and surmount the long-standing opposition to listing shark species that are taken at a commercial scale."

The oceanic whitetip shark, porbeagle, three species of hammerheads, and both manta rays ? all classified as threatened on the IUCN Red List -- will now be added to CITES Appendix II, which prompts permits to ensure exports are sustainable and legal. The only sharks listed under CITES previous to this meeting ? basking, whale, and white sharks ? are not taken in the high volumes associated with the newly listed sharks. The freshwater sawfish will be transferred from Appendix II to I, where all other sawfishes are listed, thereby completing a global ban on international commercial trade in these critically endangered species.

"We're grateful to proponent governments for recognizing the value of thriving shark and ray populations, and for championing sound proposals," said Ania Budziak, Project AWARE's Associate Director. "We're proud that the divers' voice has contributed to achieving this key milestone in shark and ray conservation."

Proponents of the various listing proposals include the 27 Member States of the EU, Australia, Brazil, Colombia, Comoros, Costa Rica, Croatia, Ecuador, Egypt, Honduras, Mexico, and the USA. The shark and ray proposals received more than the two-thirds majority of votes necessary for adoption while the sawfish listing succeeded by consensus.

"With relief that the Committee decisions were not overturned, we now turn our focus to the essential phase of their implementation," said Sonja Fordham, President of Shark Advocates International. "We urge all Parties to recognize the urgency of the shark and ray plight and to begin this work to ensure the sustainability of international trade in newly listed species, as a matter of priority."

###

Wildlife Conservation Society: http://www.wcs.org

Thanks to Wildlife Conservation Society for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/127318/CITES_makes_historic_decision_to_protect_sharks_and_rays

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Japanese P2 study shows potential of combined vaccine and steroid drug in castration resistant PCa

Japanese P2 study shows potential of combined vaccine and steroid drug in castration resistant PCa [ Back to EurekAlert! ] Public release date: 15-Mar-2013
[ | E-mail | Share Share ]

Contact: Ivanka Moerkerken
i.moerkerken@uroweb.org
31-026-389-0680
European Association of Urology

Arnhem, 11 March 2013- Multi-peptide vaccination therapy combined with the low-dose steroid drug dexamethasone shows promise in treating chemotherapy-naive castration resistant prostate cancer (CRPC) patients.

The study, which won the third prize for best abstract in oncology at the 28th European Association of Urology Congress held in Milan, Italy from 15 to 19 March, showed the promising benefit of this combination therapy in patients who are chemotherapy-naive or those not yet exposed to specific antigens.

"Results of our randomized prospective study suggest that multi-peptide vaccination therapy in combination with low dose dexamethasone has the therapeutic potential as a safe and efficient option for chemotherapy-nave CRPC patients," said lead study author Dr. Takahiro Kimura, of the Jikei University School of Medicine, Dept. of Urology, Tokyo, Japan.

Since immunotherapy does not have a strong ability to decrease tumour burden, it is considerably difficult to evaluate the full extent of a significant therapeutic effect with peptide vaccines, explained Kimura. "Taking this into consideration, the present evidence is promising," he said.

The researchers have previously developed MHC class-I restricted peptide vaccines for prostate cancer and carried out a phase 1 trial to assess safety and immunological evaluation. In the present study, Kimura and his colleagues conducted a randomized phase 2 study to evaluate the efficacy of peptide vaccine therapy for chemotherapy nave CRPC patients.

Early stage CRPC (PSA

Kimura said that although percentage PSA decline is the same in both vaccination/dexamethasone and dexamethasone alone group, PSA-PFS was significantly longer (p

"This means that the anti-tumour immune response may play an important role in suppressing disease progression. This therapeutic strategy using peptide vaccines is likely to be comparable as that from currently developed anti-androgenic agents such as abiraterone acetate, MDV3100," Kimura noted.

Castration resistant prostate cancer is a difficult patient group to manage since although a number of therapeutic modalities have been developed, none have lived up to the full expectations and treatment options remain limited.

Kimura added that although the concept of immunotherapy for cancer is not new, recent technological advances have opened new avenues to explore and optimize peptide-based immunotherapy.

"Since the anti-tumour effects of peptide vaccination are driven by different mechanisms as those from ADT and chemotherapy, we may circumvent many of the pitfalls experienced with the current therapies. We believe that this treatment approach will be key in order to achieve a breakthrough as a new therapeutic option for CRPC," he said.

###



[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Japanese P2 study shows potential of combined vaccine and steroid drug in castration resistant PCa [ Back to EurekAlert! ] Public release date: 15-Mar-2013
[ | E-mail | Share Share ]

Contact: Ivanka Moerkerken
i.moerkerken@uroweb.org
31-026-389-0680
European Association of Urology

Arnhem, 11 March 2013- Multi-peptide vaccination therapy combined with the low-dose steroid drug dexamethasone shows promise in treating chemotherapy-naive castration resistant prostate cancer (CRPC) patients.

The study, which won the third prize for best abstract in oncology at the 28th European Association of Urology Congress held in Milan, Italy from 15 to 19 March, showed the promising benefit of this combination therapy in patients who are chemotherapy-naive or those not yet exposed to specific antigens.

"Results of our randomized prospective study suggest that multi-peptide vaccination therapy in combination with low dose dexamethasone has the therapeutic potential as a safe and efficient option for chemotherapy-nave CRPC patients," said lead study author Dr. Takahiro Kimura, of the Jikei University School of Medicine, Dept. of Urology, Tokyo, Japan.

Since immunotherapy does not have a strong ability to decrease tumour burden, it is considerably difficult to evaluate the full extent of a significant therapeutic effect with peptide vaccines, explained Kimura. "Taking this into consideration, the present evidence is promising," he said.

The researchers have previously developed MHC class-I restricted peptide vaccines for prostate cancer and carried out a phase 1 trial to assess safety and immunological evaluation. In the present study, Kimura and his colleagues conducted a randomized phase 2 study to evaluate the efficacy of peptide vaccine therapy for chemotherapy nave CRPC patients.

Early stage CRPC (PSA

Kimura said that although percentage PSA decline is the same in both vaccination/dexamethasone and dexamethasone alone group, PSA-PFS was significantly longer (p

"This means that the anti-tumour immune response may play an important role in suppressing disease progression. This therapeutic strategy using peptide vaccines is likely to be comparable as that from currently developed anti-androgenic agents such as abiraterone acetate, MDV3100," Kimura noted.

Castration resistant prostate cancer is a difficult patient group to manage since although a number of therapeutic modalities have been developed, none have lived up to the full expectations and treatment options remain limited.

Kimura added that although the concept of immunotherapy for cancer is not new, recent technological advances have opened new avenues to explore and optimize peptide-based immunotherapy.

"Since the anti-tumour effects of peptide vaccination are driven by different mechanisms as those from ADT and chemotherapy, we may circumvent many of the pitfalls experienced with the current therapies. We believe that this treatment approach will be key in order to achieve a breakthrough as a new therapeutic option for CRPC," he said.

###



[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-03/eaou-jps031113.php

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